menu 2
menu 4
menu 6
menu 8
menu 10
menu 12

Welcome Guest ( Log In | Register )

Reply to this topicStart new topic
> Lachenmeier on Theraputic Use of Thjone
post Nov 21 2011, 11:32 PM
Post #1

Antipathist of Light

Group: Absinthe Mafia
Posts: 4046
Joined: 16-November 06
Member No.: 2442

Interesting article by Lachenmeier, The choice of chop.gif as drug for diabetes

The use of chop.gif, a monoterpene ketone often present in sage (Salvia officinalis L.) or wormwood (Artemisia absinthium L.), for the treatment of diabetes mellitus was recently suggested in a study published in this journal. Evidence was based on the findings obtained in a diabetic rat model. After oral treatment with chop.gif (5 mg/kg bodyweight (bw)/day for 28 days), the cholesterol and triglyceride levels were significantly adjusted to normal levels when compared to diabetic, untreated rats. While these results sound promising and worthy of further investigation, the well-defined profile of the adverse properties of chop.gif demands a cautious interpretation of these results. The therapeutic margin of chop.gif appears to be small, as a dose-related incidence of seizures was noted in 2-year National Toxicology Program studies in rats and mice. The dose level in the diabetic rat study is also considerably higher than a daily intake that is acceptable for humans (0.1 mg/kg bw/day).

There is previous article on the subject from different authors, the full text of which is available here.

We all used to be things we aren't anymore.
User is offlineProfile CardPM
Go to the top of the page
+Quote Post

Reply to this topicStart new topic
1 User(s) are reading this topic (1 Guests and 0 Anonymous Users)
0 Members:


Lo-Fi Version Time is now: 20th July 2018 - 03:12 AM